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  • Writer's pictureDiane Barker

Knowledge Matters:The Microbiome

The Steep Costs of Disrupting

Gut-Barrier Harmony

From Ayurveda to the teachings of Hippocrates, medicine's earliest traditions advanced a belief that the gut was the foundation of all health and disease. It wasn't until recently, however, that Western medicine has adopted the notion of gut-barrier dysfunction as a pathologic phenomenon critical to not only digestive health but also chronic allergic, inflammatory, and autoimmune disease.

To learn more, read on

The microbiome is the constellation of microscopic organisms that call the human body home, and its clinical implications are becoming increasingly clear to physicians.

This video examines how the trillions of microorganisms that live on and inside our bodies may hold the key to preventing and even treating a host of conditions, ranging from gastrointestinal illnesses to metabolic and neuropsychiatric disorders to cancer.

Where is the "Microbiome Revolution" Headed Next?

Human microbiome research has progressed in leaps and bounds over the past decades, from pivotal studies begun in the 1970s to the launch of the Human Microbiome Project in 2007. Breakthroughs have laid the groundwork for more recent clinical applications, such as fecal microbiota transplantation (FMT), and advanced techniques to explore new therapeutic pathways. Yet the "microbiome revolution" is just getting started, according to professor Martin J. Blaser, MD, one of the field's pioneers.

Martin J. Blaser, MD

In this interview, which has been condensed and edited for clarity, Blaser discusses where we're at now and where he sees the microbiome field evolving in the coming years.

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